VACS Index Information and VACS Calculator

VACS Index Prognostic Accuracy for Mortality

  • Tate JP, Justice AC, Hughes MD, Bonnet F, Reiss P, Mocroft A, Nattermann J, Lampe FC, Bucher HC, Sterling TR, Crane HM, Kitahata MM, May M, Sterne JA. The VACS Index: An internationally generalizable risk index for mortality after one year of antiretroviral therapy. AIDS. 2012 Oct 22. PMID: 23095314
  • Akgun KM, Tate JP, Pisani MA, et al. Medical intensive care unit (MICU) admission dianoses and outcomes in HIV-infected and uninfected Veterans in the combination antiretroviral era. Critical Care Med. (in press)
  • Justice AC, McGinnis KA, Skanderson M et al. Towards a combined prognostic index for survival in HIV infection: the role of 'non-HIV' biomarkers. HIV Med 2009. PMID: 19751364. PMCID: PMC3077949
  • Justice AC, Freiberg MS, Tracy R, Kuller L, Tate JP, Goetz MB, Fiellin DA, Vanasse GJ, Butt AA, Rodriguez-Barradas MC, Gibert C, Oursler KA, Deeks SG, Bryant K, and the VACS Project Team. Does an index composed of clinical data reflect effects of inflammation, coagulation, and monocyte activation on mortality among those aging with HIV? Clin Infect Dis 2012;54:984-994. PMID: 22337823. PMCID: PMC3297653
  • Justice AC. HIV and aging: time for a new paradigm curr HIV/AIDS rep (2010) 7:69-76. PMID: 20425560
  • Justice AC, Tate JP, Freiberg MS, Rodriquez-Barradas MC, Tracy R. Reply to Chow et al, Clin Infect Dis 2012.  
  • Tate JP, Justice AC, for the VACS Project Team. Change in a prognostic index for survival in HIV infection after one year on cART by level of adherence [abstract] 48th Annual Meeting of the Infectious Disease Society of America 2010. LinkAbstract
  • Justice AC, Modur S, Tate JP, Althoff KN, Gange SJ, Jacobson LP, Gebo K, Kitahata M, Horberg M, Napravnik S, for the NA-ACCORD and VACS Project Teams. A prognostic index for those aging with HIV: extension of the VACS index to those on cART. 18th Conference on Retroviral and Opportunistic Infections 2011. LinkAbstract
  • Tate JP, Freiberg MS,  Justice AC. Do risk factors for cardiovascular disease improve VACS Index predition of all cause mortality?  16th International Workshop on HIV Observational Databases. Abstract #16 Abstract

VACS Index Prognostic Accuracy for Morbidity

  • Akgun KM, Gordon K, Pisani M, Fried T, McGinnis KA, Tate JP, Butt AA, Gibert CL, Huang L, Rodriguez-Barradas MC, Rimland D, Justice AC, Crothers K.J Acquir Immune Defic Syndr. 2012 Oct 29. [Epub ahead of print] PMID: 23111572
  • Marquine MJ, Moore DJ, Gouaux DJ, Rooney A, Woods SP, Letendre SL, Ellis RJ, Grant I. Higher veterans aging cohort study (VACS) index scored are associated with concurrent risk of neurocognitive impairment. [abstract] 3rd International Workshop on HIV and Aging 2012. Abstract O_03.
  • Justice AC, Freiberg MS, Tracy R, Kuller L, Tate JP, Goetz MB, Fiellin DA, Vanasse GJ, Butt AA, Rodriguez-Barradas MC, Gibert C, Oursler KA, Deeks SG, Bryant K, and the VACS Project Team.. Does an index composed of clinical data reflect effects of inflammation, coagulation, and monocyte activation on mortality among those aging with HIV? Clin Infect Dis 2012;54:984-994. PMID: 22337823. PMCID: PMC3297653
  • Justice AC, Tate JP, Freiberg MS, Rodriquez-Barradas MC, Tracy R. Reply to Chow et al, Clin Infect Dis 2012.   
  • Erlandson KM, Allshouse AA, Jankowski C. Prospective comparison of three functional assessments with the Veteran's Aging Cohort Study index in virologically suppressed HIV-infected adults [abstract] 2nd International Workshop on HIV and Aging 11 A.D.;abstract #8 
  • Oursler K, Tate J, Gill T, Crothers K, Brown T, Crystal S, Womack J, Leaf D, Sorkin J, Justice A. Comorbidity is predictive of muscle strength in HIV-infected veterans: results from the VACS index. 19th Conference on Retroviral and Opportunistic Infections 2011. LinkAbstract
  • Womack JA, Goulet JL, Gibert C, Brandt C, Gulanski B, Rimland D, Rodriguez-Barradas MC, Tate JP, Yin MT, Justice AC for the Veterans Aging Cohort Study Project Team. Proton Pump Inhibitor and Protease Inhibitor Use are Associated with Fragility Fracture Risk in HIV Infected Male Veterans. IAS 2012Abstact

Use of VACS Index as an Outcome Measure

  • Kyriakides TC, Kirkwood KA, Brown ST, Justice AC, Tate JP. The VACS index score as an alternative endpoint in HIV/AIDS studies. Society for Clinical Trials 33rd Annual Meeting 2012. Link

Responsiveness of VACS Index to Change in Risk

  • Akgun KM, Pisani MA, Fried TR et al. Risk Factors for Medical Intensive Care Unit Admission in HIV Infected Veterans [abstract] American Throacic Society 2010. Link
  • Tate JP, Justice AC. Do risk factors for mortality change with time on antiretroviral therapy? 48th Annual Meeting of the Infectious Disease Society of America 2010. LinkAbstract 
  • Tate JP, Justice AC, for the VACS Project Team. Change in a prognostic index for survival in HIV infection after one year on cART by level of adherence [abstract] 48th Annual Meeting of the Infectious Disease Society of America 2010. LinkAbstract
  • Kyriakides TC, Kirkwood KA, Brown ST, Justice AC, Tate JP. The VACS index score as an alternative endpoint in HIV/AIDS studies. Society for Clinical Trials 33rd Annual Meeting 2012. Link